Prempro: The Disturbing Facts

Prempro Disturbing Facts Drug Toxic Chemicals

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Prempro: The Disturbing Facts

Prempro is a combination therapy of the estrogen and progesterone replacement drugs generally referred to as hormone replacement therapy. Marketed by Wyeth Pharmaceuticals, the drug has been linked to increased rates of breast cancer and thousands of lawsuits have been filed against the company. View All Prempro Articles

Attorney Bryan Aylstock
In a recent interview, Bryan Aylstock, a Florida attorney whose firm protects the rights of consumers who are seriously injured due to defective drugs such as Prempro, provided the following helpful consumer information about the drug, its link to breast cancer and the increasing number of lawsuits being filed against the manufacturer:
What is Prempro?
Prempro is a combination therapy of the estrogen and progesterone replacement drugs generally referred to as hormone replacement therapy. These drugs are used mainly for post-menopausal women to help replace some of the hormones that become deficient during that time. They became very popular in the 1970s and 1980s and continued to be used through the 2000’s.
Prempro itself is a trade name drug for a Wyeth product that was a combination of both estrogen and progesterone, but in one pill. The Prem being for Premarin and the Pro being for progesterone. There are a number of other drugs that are used in combination. Doctors did not have to prescribe the Prempro pill. They could have also prescribed other combination therapies, such as Premphase, two different pills with Premarin and Provera or others.
Prempro’s link to breast cancer
The issue with these hormone replacement combo therapy drugs is the risk of breast cancer, which was known by the drug companies for a long time before it became known to the general public. That has come out through internal documents that have been now made public in the various trials that have occurred involving these drugs.
The general public, and the physicians who were prescribing this combo therapy, really had no way to know of the increased risk of breast cancer, particularly with these combination therapies, until the World Health Initiative (WHI) actually stopped a study that it was doing on these drugs in 2002. It was an unusual step for them to discontinue the study midstream, but they did it because they were seeing alarming rates of breast cancer in the exposed group of these combination hormone replacement drugs.
Why the WHI study was so important
Following the WHI study, the number of women who were taking this combination therapy fell off dramatically in the United States. That is important because a lot of the scientific evidence that has come out since then has confirmed the findings of the World Health Initiative study. That study was based upon large-population samples where the scientists have actually looked at the rates of breast cancer in the United States and have found that they have dropped fairly dramatically since the use of these combination drugs has declined. So, there’s a very strong causal link between the use of this combination therapy and the risk of breast cancer.
Litigation: Thousands of cases currently filed
In terms of the litigation, there are thousands of cases currently filed. Thus far, only a handful of these have been tried. However, now that those internal documents have become public, we’ve been able to show juries the evidence – which has resulted in multi-million dollar verdicts. In fact, the last trial resulted in an award of over $100 million.
So, this litigation has matured and individual cases have gotten stronger, both from a scientific evidence and liability standpoint. In other words, we’ve increased our ability to show that drug companies who were making money off these drugs, literally billions of dollars, knew that they had a problem and intentionally, or at least negligently, failed to disclose those problems to the individuals that were taking the drugs.
I would encourage anyone who took this combination therapy to make sure that they’re checked regularly for breast cancer. If they develop breast cancer, talk with an attorney about their legal rights and what they can do to hold the drug companies accountable for what they did in conjunction with this product.
If you or a loved one has been injured due to the use of Prempro, contact an attorney to discuss your situation. The consultation is free, without obligation and strictly confidential. To contact a qualified attorney whose practice focuses in this area of the law, please click here.
Suffered harm from Prempro? You may have a lawsuit. Click here, for a top rated law firm to evaluate your legal rights.

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Study Shows Dangerous Effects of Prempro Linger For Years

Study Shows Dangerous Effects Of Prempro Linger For Years Drug Toxic Chemicals

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Study Shows Dangerous Effects of Prempro Linger For Years

A recent study in the Journal of the American Medical Association (AMA) shows that the dangerous effects of Prempro use linger for nearly 2 ½ years after patients stop taking the drug. Prempro use has been linked to increased rates of heart attacks, blood clots, strokes and breast cancer.View All Prempro Articles

The study
According to news reports, the National Heart, Lung and Blood Institute studied 15,730 women who participated in a hormone replacement therapy (HRT) study conducted by the Women’s Health Initiative (WHI) several years ago that was halted due to the increased risks of heart disease, stroke and breast cancer.
The women took the drug Prempro, an HRT drug manufactured by Wyeth Pharmaceuticals, for an average of 5 ½ years. Doctors reported that the risks associated with the drug did eventually decrease, but generally not until two to three years afterwards – leaving women who thought they were safe at increased risks of serious injury or death. Researchers found 24% more cancers among women who took Prempro versus a placebo and reported that breast tumors were the most common type of cancer that developed from use of the drug.
Prempro sales drop – cancer rates decrease
Is it merely a coincidence that cancer rates have decreased as Prempro sales have decreased? Industry analysts don’t think so. Prempro, which is a combination of premarin and progesterone (hence the name Prem-pro), was widely used by women in this country for many years. Sales of the drug have declined from a reported $2 billion per year to $1 billion per year since 2002 – which, coincidentally, is when the original WHI study was halted and made public. Bryan Aylstock, a Florida attorney whose firm protects the rights of consumers who are seriously injured due to defective drugs such as Prempro, agrees. He says that the number of women who were taking this combination therapy fell off dramatically in the United States following the WHI study. He told us:
The WHI study was based upon large-population samples where the scientists have actually looked at the rates of breast cancer in the United States and have found that they have dropped fairly dramatically since the use of these combination drugs has declined. So, there’s a very strong causal link between the use of this combination therapy and the risk of breast cancer.
If you or a loved one has been injured due to the use of Prempro, contact an attorney to discuss your situation. The consultation is free, without obligation and strictly confidential. To contact a qualified attorney whose practice focuses in this area of the law, please click here.

Read more for related video clips.

Continue reading “Study Shows Dangerous Effects of Prempro Linger For Years”